Public Charity

The Broad Institute Inc

The Broad Institute Inc is a nonprofit organization categorized as Public Charity based in Cambridge, MA. Its most recent IRS filing (2025) reports revenue of $846.1M, expenses of $799.0M, total assets of $3.5B. Imperigo tracks 379 reported grant relationships connected to this organization totaling approximately $712.9M.

EIN: 263428781 Cambridge, MA Birth Defects & Genetic Diseases Research NTEE: H20 Latest filing: 2025
Total Revenue$846.1M
Total Expenses$799.0M
Total Assets$3.5B
Grant Records379
Funding Total$712.9M
Filing Years2021–2025

Mission

THE MISSION OF THE BROAD INSTITUTE IS TO PROPEL PROGRESS IN BIOMEDICINE, THROUGH RESEARCH AIMED AT THE UNDERSTANDING AND TREATMENT OF DISEASE AND THE DISSEMINATION OF SCIENTIFIC KNOWLEDGE TO THE SCIENTIFIC COMMUNITY TO BENEFIT THE PUBLIC. WE ARE A RESEARCH ORGANIZATION DEDICATED TO UNDERSTANDING THE ROOTS OF DISEASE AND CLOSING THE GAP BETWEEN NEW BIOLOGICAL INSIGHTS AND IMPACT FOR PATIENTS.

Sample Grants Received

2025
INVESTIGATING ALZHEIMER'S DISEASE-ASSOCIATED MEMBRANE BIOLOGY IN MICROGLIA AND NEURONS
$230,000
2025
In conjunction with The Children's Hospital of Philadelphia, Base Editing for the Treatment and Prevention of Dravet Syndrome. This project aims to develop a precision gene-editing approach using base editing technology to directly correct disease-causing mutations at the DNA level using a mouse model of Dravet syndrome. The goal is to create a durable, potentially one-time treatment that can restore normal gene function without introducing double-strand DNA breaks. Researchers are working to optimize delivery systems, improve editing efficiency, and evaluate safety in relevant models. Ultimately, the project seeks to establish a foundation for preventive or early-intervention therapies that address the root genetic cause rather than managing symptoms.
$100,000
2025
PEDIATRIC CANCER RESEARCH
$43,332
$10,300,450
$7,007,282

Showing up to 5 of 379 total records — full history available with membership.

Officers & Directors

Director Alan Garber
Director Arthur Levinson
Director (Beg 10/24) Benjamin Ebert
Senior Counsel/Clerk Corrina L Hale
Chief Operating Officer Dan Shore
Director David Baltimore

Officer compensation and complete director data available with membership.

Top Grant Purposes

HEALTH
$207,283,844 11 grants
TO PROVIDE SUPPORT FOR THE ORGANIZATION.
$163,000,000 4 grants
Research
$58,770,347 27 grants
RESEARCH
$36,220,528 34 grants
For grant recipient's exempt purposes
$22,906,430 9 grants

Financial Trends

Year Revenue Expenses Assets
2025 $846.1M $799.0M $3.5B
2024 $831.1M $752.5M $2.9B
2023 $860.4M $730.5M $2.7B
2022 $1.1B $826.3M $2.7B
2021 $1.3B $862.0M $2.6B

Between 2021 and 2025, reported annual revenue declined from $1.3B to $846.1M (-37%), with total assets most recently reported at $3.5B.

Interactive year-over-year charts and full filing details available with membership.

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