Public Charity

The Broad Institute Inc

The Broad Institute Inc is a nonprofit organization categorized as Public Charity based in Cambridge, MA. Its most recent IRS filing (2025) reports revenue of $846.1M, expenses of $799.0M, total assets of $3.5B. Imperigo tracks 390 reported grant relationships connected to this organization totaling approximately $722.9M.

EIN: 263428781 Cambridge, MA Birth Defects & Genetic Diseases Research NTEE: H20 Latest filing: 2025
Total Revenue$846.1M
Total Expenses$799.0M
Total Assets$3.5B
Grant Records390
Funding Total$722.9M
Filing Years2021–2025

Mission

THE MISSION OF THE BROAD INSTITUTE IS TO PROPEL PROGRESS IN BIOMEDICINE, THROUGH RESEARCH AIMED AT THE UNDERSTANDING AND TREATMENT OF DISEASE AND THE DISSEMINATION OF SCIENTIFIC KNOWLEDGE TO THE SCIENTIFIC COMMUNITY TO BENEFIT THE PUBLIC. WE ARE A RESEARCH ORGANIZATION DEDICATED TO UNDERSTANDING THE ROOTS OF DISEASE AND CLOSING THE GAP BETWEEN NEW BIOLOGICAL INSIGHTS AND IMPACT FOR PATIENTS.

Where $100 goes at The Broad Institute Inc

How The Broad Institute Inc divides every $100 it spends, from its own Form 990 filings, averaged across 9 years.

$82 Programs the work itself
$17 Management running the organization
$1 Fundraising raising the next dollar

Inside the $82 for programs

$82
The Broad Institute operates for educational and scientific purposes to improve human health by using genomics to advance the understanding of the biology and treatment of human disease…
All program spending · Reported in the filing: 2,200 participants; 3,000 students; 18 students
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Source: Form 990 filings with the IRS, latest fiscal year 2025. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.

Sample Grants Received

$4,824,668
2025
RESEARCH GRANT
$299,615
2025
INVESTIGATING ALZHEIMER'S DISEASE-ASSOCIATED MEMBRANE BIOLOGY IN MICROGLIA AND NEURONS
$230,000
2025
In conjunction with The Children's Hospital of Philadelphia, Base Editing for the Treatment and Prevention of Dravet Syndrome. This project aims to develop a precision gene-editing approach using base editing technology to directly correct disease-causing mutations at the DNA level using a mouse model of Dravet syndrome. The goal is to create a durable, potentially one-time treatment that can restore normal gene function without introducing double-strand DNA breaks. Researchers are working to optimize delivery systems, improve editing efficiency, and evaluate safety in relevant models. Ultimately, the project seeks to establish a foundation for preventive or early-intervention therapies that address the root genetic cause rather than managing symptoms.
$100,000
$50,000

Showing up to 5 of 390 total records — full history available with membership.

Officers & Directors

Director Alan Garber
Director Arthur Levinson
Director (Beg 10/24) Benjamin Ebert
Senior Counsel/Clerk Corrina L Hale
Chief Operating Officer Dan Shore
Director David Baltimore

Officer compensation and complete director data available with membership.

Top Grant Purposes

Health & Medicine
$273,024,183 88 grants
General Support
$243,497,210 86 grants
Research & Policy
$176,087,444 159 grants
Fundraising & Sponsorship
$13,271,711 13 grants
Education
$7,772,495 14 grants

Financial Trends

Year Revenue Expenses Assets
2025 $846.1M $799.0M $3.5B
2024 $831.1M $752.5M $2.9B
2023 $860.4M $730.5M $2.7B
2022 $1.1B $826.3M $2.7B
2021 $1.3B $862.0M $2.6B

Between 2021 and 2025, reported annual revenue declined from $1.3B to $846.1M (-37%), with total assets most recently reported at $3.5B.

Interactive year-over-year charts and full filing details available with membership.

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