Public Charity

INSTITUTE FOR SYSTEMS BIOLOGY

INSTITUTE FOR SYSTEMS BIOLOGY is a nonprofit organization categorized as Public Charity based in RENTON, WA. Its most recent IRS filing (2024) reports revenue of $42.3M, expenses of $47.6M, total assets of $109.3M. Imperigo tracks 96 reported grant relationships connected to this organization totaling approximately $16.4M.

EIN: 912003593 RENTON, WA Latest filing: 2024
Total Revenue$42.3M
Total Expenses$47.6M
Total Assets$109.3M
Grant Records96
Funding Total$16.4M
Filing Years2019–2024

Mission

NON-PROFIT RESEARCH INSTITUTE TO ADVANCE A SYSTEMS (OR HOLISTIC AND CROSS-DISCIPLINARY) APPROACH TO SCIENCE; PERSONALIZED MEDICINE; GLOBAL HEALTH & ENVIRONMENTAL SUSTAINABILITY; SCIENCE EDUCATION; & THE PIONEERING & INVENTION OF BIOLOGICAL & TECHNOLOGICAL METHODS & TOOLS.

Sample Grants Received

EVERY CURE INC
2024
ISB WILL CURATE, EVALUATE, AND INTEGRATE LARGE BIOMEDICAL DATASETS INTO EVERY CURE'S KNOWLEDGE GRAPH, FOCUSING ON DATA QUALITY AND ONTOLOGY HARMONIZATION. THEY WILL PERFORM MANUAL CURATION, CROSS-VALIDATION, AND DEVELOPMENT OF PROTOCOLS TO ENSURE RELIABLE DRUG, DISEASE, AND MOLECULAR ASSOCIATIONS. THEIR WORK ENSURES THE SPOKE DATABASE AND OTHER KEY SOURCES ARE INCORPORATED INTO A ROBUST COMPUTATIONAL FRAMEWORK FOR DRUG REPURPOSING.
$309,022
SAGE BIONETWORKS
2024
CRI IMMUNE ATLAS 4 AND 5: PLATFORM FOR IMMUNE-ONCOLOGY RESEARCH AND DATA SHARING. EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DESIGN AND PERFORM CROSS-PROJECT ANALYSIS FOCUSED ON HARNESSING SYSTEMS BIOLOGY-BASED TECHNIQUES, SUCH AS MULTI-OMIC DATA INTEGRATION, NETWORK ANALYSIS, MACHINE LEARNING, AND STATISTICAL MODELING, TO INVESTIGATE BOTH AGING AND DISEASE, AS WELL AS THE INTERPLAY BETWEEN THEM.
$204,222
SAGE BIONETWORKS
2024
EXCEPTIONAL LONGEVITY: PROVIDE SCIENTIFIC OVERSIGHT OF A WORKING GROUP CONDUCTING CROSS-PROJECT ANALYSES USING SYSTEMS BIOLOGY APPROACHES TO STUDY AGING, ALZHEIMERS DISEASE, AND THEIR INTERACTIONS.
$114,897
MAYO CLINIC GROUP RETURN
2024
SUPPORT CHARITABLE PURPOSE
$74,577
MAYO CLINIC
2024
SUPPORT CHARITABLE PURPOSE
$19,130

Showing up to 5 of 96 total records — full history available with membership.

Officers & Directors

DIRECTOR Amy Compton-Phillips Md
DIRECTOR OF DATA SCIENCE Andrew Magis
DIRECTOR Ari Robicsek Md
DIRECTOR Brian V Turner
BOARD CHAIR Charles Watts Md
DIRECTOR Craig Mundie

Officer compensation and complete director data available with membership.

Top Grant Purposes

PEDIATRIC MEDICAL RESEARCH GRANT SUBAWARD
$2,208,059 6 grants
SPONSORED RESEARCH SUB-AWARD
$2,000,244 6 grants
SUPPORT RESEARCH IN FIELD OF CANCER IMMUNOTHERAPY
$1,537,803 3 grants
SUPPORT CHARITABLE PURPOSE
$1,122,158 4 grants
Research
$977,216 4 grants

Financial Trends

Year Revenue Expenses Assets
2024 $42.3M $47.6M $109.3M
2023 $43.6M $46.8M $121.2M
2022 $37.1M $42.0M $126.6M
2020 $39.8M $40.5M $80.2M
2019 $36.2M $41.0M $73.3M

Between 2019 and 2024, reported annual revenue grew from $36.2M to $42.3M (+17%), with total assets most recently reported at $109.3M.

Interactive year-over-year charts and full filing details available with membership.

See the full picture for INSTITUTE FOR SYSTEMS BIOLOGY

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