Public Charity

INSTITUTE FOR SYSTEMS BIOLOGY

INSTITUTE FOR SYSTEMS BIOLOGY is a nonprofit organization categorized as Public Charity based in RENTON, WA. Its most recent IRS filing (2024) reports revenue of $42.3M, expenses of $47.6M, total assets of $109.3M. Imperigo tracks 101 reported grant relationships connected to this organization totaling approximately $17.1M.

EIN: 912003593 RENTON, WA Biological & Life Sciences NTEE: U50 Latest filing: 2024
Total Revenue$42.3M
Total Expenses$47.6M
Total Assets$109.3M
Grant Records101
Funding Total$17.1M
Filing Years2019–2024

Mission

NON-PROFIT RESEARCH INSTITUTE TO ADVANCE A SYSTEMS (OR HOLISTIC AND CROSS-DISCIPLINARY) APPROACH TO SCIENCE; PERSONALIZED MEDICINE; GLOBAL HEALTH & ENVIRONMENTAL SUSTAINABILITY; SCIENCE EDUCATION; & THE PIONEERING & INVENTION OF BIOLOGICAL & TECHNOLOGICAL METHODS & TOOLS.

Where $100 goes at Institute for Systems Biology

How Institute for Systems Biology divides every $100 it spends, from its own Form 990 filings, averaged across 7 years.

$70 Programs the work itself
$29 Management running the organization
$1 Fundraising raising the next dollar

Inside the $70 for programs

$70
At providence, we use our voice to advocate for vulnerable populations and needed reforms in health care
All program spending · Reported in the filing: 1,014 clinics; 55 awards; 24 teachers
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Source: Form 990 filings with the IRS, latest fiscal year 2024. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.

Sample Grants Received

2025
CURATE, EVALUATE AND INTEGRATE LARGE BIOMEDICAL DATASETS
$391,997
2024
ISB WILL CURATE, EVALUATE, AND INTEGRATE LARGE BIOMEDICAL DATASETS INTO EVERY CURE'S KNOWLEDGE GRAPH, FOCUSING ON DATA QUALITY AND ONTOLOGY HARMONIZATION. THEY WILL PERFORM MANUAL CURATION, CROSS-VALIDATION, AND DEVELOPMENT OF PROTOCOLS TO ENSURE RELIABLE DRUG, DISEASE, AND MOLECULAR ASSOCIATIONS. THEIR WORK ENSURES THE SPOKE DATABASE AND OTHER KEY SOURCES ARE INCORPORATED INTO A ROBUST COMPUTATIONAL FRAMEWORK FOR DRUG REPURPOSING.
$309,022
2024
CRI IMMUNE ATLAS 4 AND 5: PLATFORM FOR IMMUNE-ONCOLOGY RESEARCH AND DATA SHARING. EXCEPTIONAL LONGEVITY DATA MANAGEMENT AND COORDINATING CENTER, DESIGN AND PERFORM CROSS-PROJECT ANALYSIS FOCUSED ON HARNESSING SYSTEMS BIOLOGY-BASED TECHNIQUES, SUCH AS MULTI-OMIC DATA INTEGRATION, NETWORK ANALYSIS, MACHINE LEARNING, AND STATISTICAL MODELING, TO INVESTIGATE BOTH AGING AND DISEASE, AS WELL AS THE INTERPLAY BETWEEN THEM.
$204,222
2024
Research Support/Subawards
$186,871
2024
EXCEPTIONAL LONGEVITY: PROVIDE SCIENTIFIC OVERSIGHT OF A WORKING GROUP CONDUCTING CROSS-PROJECT ANALYSES USING SYSTEMS BIOLOGY APPROACHES TO STUDY AGING, ALZHEIMERS DISEASE, AND THEIR INTERACTIONS.
$114,897

Showing up to 5 of 101 total records — full history available with membership.

Officers & Directors

DIRECTOR Amy Compton-Phillips Md
DIRECTOR OF DATA SCIENCE Andrew Magis
DIRECTOR Ari Robicsek Md
DIRECTOR Brian V Turner
BOARD CHAIR Charles Watts Md
DIRECTOR Craig Mundie

Officer compensation and complete director data available with membership.

Top Grant Purposes

Health & Medicine
$6,692,855 22 grants
General Support
$3,533,065 33 grants
Fundraising & Sponsorship
$2,825,033 12 grants
Research & Policy
$2,331,840 16 grants
Youth Development
$60,000 2 grants

Financial Trends

Year Revenue Expenses Assets
2024 $42.3M $47.6M $109.3M
2023 $43.6M $46.8M $121.2M
2022 $37.1M $42.0M $126.6M
2020 $39.8M $40.5M $80.2M
2019 $36.2M $41.0M $73.3M

Between 2019 and 2024, reported annual revenue grew from $36.2M to $42.3M (+17%), with total assets most recently reported at $109.3M.

Interactive year-over-year charts and full filing details available with membership.

See the full picture for INSTITUTE FOR SYSTEMS BIOLOGY

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