Public Charity

DDX3X FOUNDATION

DDX3X FOUNDATION is a Public Charity headquartered in WILMINGTON, DE. Financial data from the 2025 filing: $387K revenue, $453K expenses, $74K total assets. 27 publicly reported grants to this organization, totaling roughly $1.1M, appear in IRS filings.

EIN: 811159359 WILMINGTON, DE Fund Raising & Fund Distribution NTEE: G12 Latest filing: 2025
Total Revenue$387K
Total Expenses$453K
Total Assets$74K
Grant Records27
Funding Total$1.1M
Filing Years2021–2025

Mission

OUR MISSION IS TO CONNECT FAMILIES, RESOURCES, AND THE MEDICAL COMMUNITY TO ADVANCE RESEARCH FOR A CURE TO DDX3X GENE MUTATIONS. OUR ULTIMATE GOAL OVER THE COMING YEARS IS TO ACCELERATE BRAIN FUNCTION IN INDIVIDUALS AFFECTED BY DDX3X THROUGH ADVANCES IN GENE THERAPY AND PHARMACEUTICALS.

Where $100 goes at Ddx3x Foundation

How Ddx3x Foundation divides every $100 it spends, from its own Form 990 filings, averaged across 5 years.

$74 Programs the work itself
$26 Management running the organization
$0 Fundraising none reported

No fundraising costs are reported. That often means fundraising runs through a separate affiliated organization that files its own return.

Inside the $74 for programs

$56
Raise awareness of ddx3x disease by holding family conferences, events, training sessions and disease awareness type gatherings
75% of program spending
$18
Raise awareness of ddx3x disease by holding family conferences, events, training sessions and disease awareness type gatherings
25% of program spending
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Source: Form 990 filings with the IRS, latest fiscal year 2025. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.

Officers & Directors

SECRETARY, T Elizabeth Berger
PRESIDENT Elizabeth Buccini
OTHER BOARD Robert Buccini

Officer compensation and complete director data available with membership.

Top Grant Purposes

Health & Medicine
$646,600 6 grants
General Support
$426,700 16 grants
Animal Welfare
$23,000 1 grant
Human & Social Services
$13,000 2 grants
Unspecified
$30,621 1 grant

Financial Trends

Year Revenue Expenses Assets
2025 $387K $453K $74K
2024 $269K $446K $140K
2023 $272K $723K $314K
2022 $583K $545K $756K
2021 $420K $226K $733K

Between 2021 and 2025, reported annual revenue declined from $420K to $387K (-8%), with total assets most recently reported at $74K.

Interactive year-over-year charts and full filing details available with membership.

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