Public Charity

Howard Hughes Medical Institute

Howard Hughes Medical Institute is a Public Charity headquartered in CHEVY CHASE, MD. Financial data from the 2025 filing: $2.0B revenue, $1.2B expenses, $29.5B total assets. IRS filings disclose 957 grants awarded by this foundation, totaling roughly $394.3M.

EIN: 590735717 CHEVY CHASE, MD Biomedicine & Bioengineering Research NTEE: H92 Latest filing: 2025
Total Revenue$2.0B
Total Expenses$1.2B
Total Assets$29.5B
Grants Given957
Grant Total$394.3M
Filing Years2021–2025

Mission

THE MISSION OF THE INSTITUTE HAS REMAINED CONSTANT SINCE ITS FOUNDING IN 1953. AS ITS RESTATED ARTICLES OF INCORPORATION STATE THE PRIMARY PURPOSE AND OBJECTIVE OF THE HOWARD HUGHES MEDICAL INSTITUTE SHALL BE THE PROMOTION OF HUMAN KNOWLEDGE BY CONDUCTING DISCOVERY RESEARCH AND SCIENCE EDUCATION, PRINCIPALLY WITHIN FIELDS ASSOCIATED WITH BASIC BIOMEDICAL SCIENCES, AND THE DISSEMINATION AND APPLICATION OF THAT KNOWLEDGE FOR THE BENEFIT OF HUMANITY.

Where $100 goes at Howard Hughes Medical Institute

How Howard Hughes Medical Institute divides every $100 it spends, from its own Form 990 filings, averaged across 9 years.

$78 Programs the work itself
$22 Management running the organization
$0 Fundraising none reported

No fundraising costs are reported. That often means fundraising runs through a separate affiliated organization that files its own return.

Inside the $78 for programs

$69
Medical research organization activities the hhmi investigator program the Howard Hughes Medical Institute's approach to biomedical research can be summarized in three words: people, not projects
88% of program spending · Reported in the filing: 31 scholars
$9
Science education, fellowships, and media programs through its science education, fellowships, and media programs, hhmi invests in individuals, initiatives, and media that advance learning and promote success in…
12% of program spending · Reported in the filing: 7,779 students; 30 students; 25 members
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Source: Form 990 filings with the IRS, latest fiscal year 2025. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.

Before you apply to Howard Hughes Medical Institute

Rarely funds new orgs 9% of recent recipients were first-time grantees (2022–2024).

Who to contact, what to include, deadlines, typical grant size and geographic focus are available with membership.

Sample Grants Given

UNIVERSITY OF CALIFORNIA SAN FRANCISCO
SAN FRANCISCO, CA · 2024
MEDICAL RESEARCH
$3,062,953
CAMBRIDGE, MA · 2024
MEDICAL RESEARCH
$2,113,215
NEW HAVEN, CT · 2024
MEDICAL RESEARCH
$1,286,366
ASHBURN, VA · 2024
SUPPORT OF K-12 SCIENCE EDUCATION ACTIVITIES
$1,000,000
REDWOOD CITY, CA · 2024
MEDICAL RESEARCH
$502,742

Showing up to 5 of 957 total records — full history available with membership.

Officers & Directors

TRUSTEE Alison F Richard Phd
VP SCIENCE LEADERSHIP AND CULTURE (THRU 05/25)/LAB HEAD Blanton Tolbert Phd
CHIEF OF STRATEGIC INITIATIVES Bodo Stern Phd
TRUSTEE, CHAIR NOM & GOV COMM Charlene Barshefsky Esq
TRUSTEE, CHAIR Clayton S Rose Phd
SENIOR GROUP LEADER/FORMER VP & CHIEF SCIENTIFIC OFFICER David E Clapham Phd

Officer compensation and complete director data available with membership.

Top Grant Purposes

Education
$113,559,068 307 grants
Health & Medicine
$84,505,657 109 grants
General Support
$67,114,636 262 grants
Research & Policy
$6,912,338 45 grants
Housing & Homelessness
$223,436 16 grants

Financial Trends

Year Revenue Expenses Assets
2025 $2.0B $1.2B $29.5B
2024 $1.8B $1.2B $27.3B
2023 $749.0M $1.1B $25.9B
2022 $2.1B $986.3M $25.9B
2021 $2.1B $954.8M $29.3B

Between 2021 and 2025, reported annual revenue declined from $2.1B to $2.0B (-4%), with total assets most recently reported at $29.5B.

Interactive year-over-year charts and full filing details available with membership.

Grant Geography

Grants from this foundation were reported to recipients in AK, AL, AR, AZ, CA, CO, and 4 other states.

AKALARAZCACOCTDCDEFL

Full geographic grant map with state-by-state breakdown available with membership.

See the full picture for Howard Hughes Medical Institute

Complete financials, all 957 grant records, officer compensation, year-over-year trend charts, a geographic grant map, and data exports — across 880,000+ organizations.

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