Mission
TO ACCELERATE FULL SPECTRUM RESEARCH TO CURE RETT SYNDROME AND EMPOWER FAMILIES WITH INFORMATION, KNOWLEDGE, AND CONNECTIVITY.
Public Charity
INTERNATIONAL RETT SYNDROME FOUNDATION
Based in CINCINNATI, OH, INTERNATIONAL RETT SYNDROME FOUNDATION operates as a Public Charity. The organization reported $4.3M in revenue, $5.2M in expenses, $4.7M in total assets for fiscal year 2025. Imperigo tracks 99 reported grant relationships connected to this organization totaling approximately $3.9M.
EIN: 311682518
CINCINNATI, OH
Fund Raising & Fund Distribution
NTEE: H12
Latest filing: 2025
Total Revenue$4.3M
Total Expenses$5.2M
Total Assets$4.7M
Grant Records99
Funding Total$3.9M
Filing Years2021–2025
Where $100 goes at International Rett Syndrome Foundation
How International Rett Syndrome Foundation divides every $100 it spends, from its own Form 990 filings, averaged across 9 years.
$85
Programs
the work itself
$7
Management
running the organization
$8
Fundraising
raising the next dollar
Inside the $85 for programs
$72
Irsf advances the full spectrum of rett syndrome research
$13
Irsf stands alongside families at every stage of the rett syndrome journey - from diagnosis through adulthood
Source: Form 990 filings with the IRS, latest fiscal year 2025. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.
Sample Grants Received
GENERAL SUPPORT
$130,000
RETT SYNDROME RESEARCH
$16,840
GENERAL SUPPORT
$14,619
GENERAL SUPPORT
$135,000
GENERAL SUPPORT
$121,805
Showing up to 5 of 99 total records — full history available with membership.
Officers & Directors
TRUSTEE
Alan Shukovsky
CHAIRMAN
David Pass Pharmd
CHIEF SCIENTIFIC OFFICER
Dominque Pichard
TRUSTEE
Joseph Horrigan Md
CHIEF EXECUTIVE OFFICER - START 4/25
Laura Hameed
TRUSTEE
Laura Stoppel Phd
Officer compensation and complete director data available with membership.
Top Grant Purposes
Financial Trends
| Year | Revenue | Expenses | Assets |
|---|---|---|---|
| 2025 | $4.3M | $5.2M | $4.7M |
| 2024 | $4.8M | $5.5M | $5.3M |
| 2023 | $4.9M | $3.7M | $6.3M |
| 2022 | $3.7M | $5.5M | $6.4M |
| 2021 | $4.1M | $4.1M | $7.4M |
Between 2021 and 2025, reported annual revenue grew from $4.1M to $4.3M (+3%), with total assets most recently reported at $4.7M.
Interactive year-over-year charts and full filing details available with membership.