Public Charity

GLOBAL DOWN SYNDROME FOUNDATION

GLOBAL DOWN SYNDROME FOUNDATION, of DENVER, CO, is a Public Charity tracked in Imperigo's IRS 990 database. The 2025 filing shows $4.7M in revenue, $4.7M in expenses, $8.7M in total assets. 102 publicly reported grants to this organization, totaling roughly $2.5M, appear in IRS filings.

EIN: 264431001 DENVER, CO Latest filing: 2025
Total Revenue$4.7M
Total Expenses$4.7M
Total Assets$8.7M
Grant Records102
Funding Total$2.5M
Filing Years2021–2025

Mission

TO SIGNIFICANTLY IMPROVE THE LIVES OF PEOPLE WITH DOWN SYNDROME THROUGH RESEARCH, MEDICAL CARE, EDUCATION AND ADVOCACY. AN IMPORTANT PART OF THIS MISSION IS TO SUPPORT THE GLOBAL AFFILIATE ORGANIZATIONS THAT WE HELPED ESTABLISH AND CONTINUE TO FUNDRAISE FOR. GLOBAL AND OUR AFFILIATES WORK TOGETHER TO ELONGATE LIFE AND DRAMATICALLY IMPROVE HEALTH OUTCOMES TO ENSURE PEOPLE WITH THE CONDITION CAN REACH THEIR TRUE POTENTIAL. GLOBAL AFFILIATES INCLUDE: CRNIC INSTITUTE FOR DOWN SYNDROME, ALZHEIMER'S & COGNITION CENTER, SIE CENTER FOR DOWN SYNDROME, AND GLOBAL ADULT CLINIC. ANOTHER IMPORTANT PART OF OUR MISSION IS TO ENGAGE IN GOVERNMENT ADVOCACY THAT LEADS TO TRANSFORMATIVE INCREASES IN GOVERNMENT FUNDING FOR DOWN SYNDROME RESEARCH AND MEDICAL CARE WHICH IN TURN WILL CREATE A PIPELINE OF YOUNG TALENT DEDICATED TO THIS POPULATION. BECAUSE OF GLOBAL'S WORK, SCIENTISTS ARE DEVELOPING BETTER METHODS TO UNDERSTAND HOW THE TRIPLICATION LEADS TO A MUCH HIGHER INCIDENCE OF CERTAIN DISEASES (FOR EXAM

Officers & Directors

DIRECTOR Charlie Monfort
DIRECTOR Frank Stephens
DIRECTOR Jamie Nielsen
DIRECTOR Jay Mills
DIRECTOR John C Mcginley
CHAIR John J Sie

Officer compensation and complete director data available with membership.

Top Grant Purposes

For grant recipient's exempt purposes
$638,225 9 grants
GENERAL PURPOSE
$159,116 6 grants
HEALTH
$152,850 5 grants
GENERAL SUPPORT
$131,012 10 grants
FOR GENERAL OPERATING SUPPORT
$127,200 2 grants

Financial Trends

Year Revenue Expenses Assets
2025 $4.7M $4.7M $8.7M
2024 $4.3M $4.7M $8.6M
2023 $3.8M $3.6M $9.1M
2022 $946K $1.2M $8.6M
2021 $3.2M $2.7M $8.3M

Between 2021 and 2025, reported annual revenue grew from $3.2M to $4.7M (+46%), with total assets most recently reported at $8.7M.

Interactive year-over-year charts and full filing details available with membership.

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