Public Charity

MYELIN REPAIR FOUNDATION INC

MYELIN REPAIR FOUNDATION INC is a Public Charity headquartered in Saratoga, CA. Financial data from the 2025 filing: $268K revenue, $513K expenses, $877K total assets. IRS filings disclose 15 grants awarded by this foundation, totaling roughly $914K.

EIN: 030485196 Saratoga, CA Private Grantmaking Foundations NTEE: T20 Latest filing: 2025
Total Revenue$268K
Total Expenses$513K
Total Assets$877K
Grants Given15
Grant Total$914K
Filing Years2020–2025

Mission

Accelerating the development of new therapeutics to prevent or repair damage to myelin caused by Multiple Sclerosis. The MRF is helping to identify biomarkers of myelin repair for use in myelin repair drug development and clinical trials

Sample Grants Given

New Haven, CT · 2024
There are two scientific research agreements with Yale for $50,000 each. The first is to validate the exosomal small RNA biomarker for MS progression in an additional validation cohort, consisting of 40 progressive and stable MS patients and then confirm the astrocyte origin of progression-associated RNAs by verifying their expression or downregulation in reactive astrocytes in autopsied brain tissue from progressive MS patients. Lastly, to test whether GLAST+ exosomes from progressive but not stable MS patients or healthy controls induce proinflammatory pathways in human iPSC-derived microglial cells that are also active in microglial populations in the brain of progressive MS patients. The second SRA aims to Develop a robust protocol to isolate OL-derived exosomes and quantify their lipid and protein content and determine the small RNA, lipid and proteomic signatures in oligodendrocyte-exosomes correlated to remyelination using samples from the RENEW optic neuritis treatment trial.
$100,000
New Youk, NY · 2023
Isolation and molecular characterization of CNS-derived, cell-specific extracellular vesicles from Multiple Sclerosis blood Samples and Identify Clostridium perfringens Epsilon Toxin Specific Extracellular Vesicle Signature in MS Patients
$150,000
Chicago, IL · 2023
Chi separation of QSM images: A new tool to image myelin vs iron in chronic MS lesions
$50,296
Oregon Health & Science University
Portland, OR · 2020
$24,964
Chicago, IL · 2019
Utilize circulating neuronally derived Evs to identify markers of neurodegeneration and repair
$125,000

Showing up to 5 of 15 total records — full history available with membership.

Officers & Directors

Director Andy Cates
Director Bobby Mehta
Director Eric Hsu
Director Jim Gidwitz
CEO Scott Johnson

Officer compensation and complete director data available with membership.

Top Grant Purposes

Isolation and molecular characterization of CNS-derived, cell-specific extracellular vesicles from Multiple Sclerosis blood Samples and Identify Clostridium perfringens Epsilon Toxin Specific Extracellular Vesicle Signature in MS Patients
$150,000 1 grant
Utilize circulating neuronally derived Evs to identify markers of neurodegeneration and repair
$125,000 1 grant
SCIENTIFIC EXPERIMENT
$106,000 2 grants
There are two scientific research agreements with Yale for $50,000 each. The first is to validate the exosomal small RNA biomarker for MS progression in an additional validation cohort, consisting of 40 progressive and stable MS patients and then confirm the astrocyte origin of progression-associated RNAs by verifying their expression or downregulation in reactive astrocytes in autopsied brain tissue from progressive MS patients. Lastly, to test whether GLAST+ exosomes from progressive but not stable MS patients or healthy controls induce proinflammatory pathways in human iPSC-derived microglial cells that are also active in microglial populations in the brain of progressive MS patients. The second SRA aims to Develop a robust protocol to isolate OL-derived exosomes and quantify their lipid and protein content and determine the small RNA, lipid and proteomic signatures in oligodendrocyte-exosomes correlated to remyelination using samples from the RENEW optic neuritis treatment trial.
$100,000 1 grant
Conduct a longitudinal study of brain endothelial and microglial cell EVs as biomarkers in MS
$74,000 1 grant

Financial Trends

Year Revenue Expenses Assets
2025 $268K $513K $877K
2024 $266K $504K $1.3M
2023 $552K $463K $1.6M
2021 $530K $236K $1.5M
2020 $267K $555K $1.4M

Between 2020 and 2025, reported annual revenue held roughly steady at around $268K, with total assets most recently reported at $877K.

Interactive year-over-year charts and full filing details available with membership.

Grant Geography

Grants from this foundation were reported to recipients in CA, CT, IL, MD, NY, OR.

CACTILMDNYOR

Full geographic grant map with state-by-state breakdown available with membership.

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