Mission
THE ALPHA-1 FOUNDATION IS COMMITTED TO FINDING A CURE FOR ALPHA-1 ANTITRYPSIN DEFICIENCY AND TO IMPROVING THE LIVES OF PEOPLE AFFECTED BY ALPHA-1 WORLDWIDE.
Public Charity
ALPHA-1 FOUNDATION INC
Based in CORAL GABLES, FL, ALPHA-1 FOUNDATION INC operates as a Public Charity. The organization reported $13.8M in revenue, $14.0M in expenses, $47.5M in total assets for fiscal year 2025. Imperigo tracks 51 reported grant relationships connected to this organization totaling approximately $12.4M.
EIN: 650585415
CORAL GABLES, FL
Public Health
NTEE: E70
Latest filing: 2025
Total Revenue$13.8M
Total Expenses$14.0M
Total Assets$47.5M
Grant Records51
Funding Total$12.4M
Filing Years2021–2025
Where $100 goes at Alpha-1 Foundation Inc
How Alpha-1 Foundation Inc divides every $100 it spends, from its own Form 990 filings, averaged across 5 years.
$83
Programs
the work itself
$8
Management
running the organization
$9
Fundraising
raising the next dollar
Inside the $83 for programs
$41
Alpha-1 research network
$17
Other alpha-1 services include patient education (materials, website, etc), a patient support network, and a targeted detection program
$9
Alpha-1 national conference
Plus 5 more programs. Cost per person served and the full program breakdown are on the full profile.
Source: Form 990 filings with the IRS, latest fiscal year 2025. Shares are from the organization's reported expenses. Data by Imperigo; not affiliated with the IRS.
Sample Grants Received
UNRESTRICTED CONTRIBUTION
$1,970,000
For grant recipient's exempt purposes
$142,100
FOR RECIPIENT'S EXEMPT PURPOSE
$100,000
$27,400
GENERAL SUPPORT
$23,210
Showing up to 5 of 51 total records — full history available with membership.
Officers & Directors
SEN DIRECTOR OF EXECUTIVE OPERATIONS & SCIENTIFIC EVENTS
Adriana Arce
DIRECTOR (AS OF 7/2024)
Alice Turner
SENIOR DIRECTOR OF CORPORATE RELATIONS
Angela T Mcbride
DIRECTOR
Ann Knebel
DIRECTOR/SECRETARY (AS OF 10/2024)
Catherine Vernon
DIRECTOR
Darrell Kotton
Officer compensation and complete director data available with membership.
Top Grant Purposes
Financial Trends
| Year | Revenue | Expenses | Assets |
|---|---|---|---|
| 2025 | $13.8M | $14.0M | $47.5M |
| 2024 | $11.6M | $10.1M | $44.5M |
| 2023 | $10.5M | $8.5M | $37.7M |
| 2022 | $10.9M | $6.4M | $35.5M |
| 2021 | $10.9M | $6.3M | $34.6M |
Between 2021 and 2025, reported annual revenue grew from $10.9M to $13.8M (+26%), with total assets most recently reported at $47.5M.
Interactive year-over-year charts and full filing details available with membership.