South Carolina · Grantmakers

Foundations That Fund Health & Medicine in South Carolina

Imperigo has identified 294 funders that made 1,951 grants totaling $234.5M to 201 health & medicine organizations in South Carolina, with a median grant of $20K. Every figure below is drawn from IRS Form 990 filings through 2025.

Health & Medicine Funding in South Carolina

Total granted $234.5M
Funders 294
Grants 1,951
Organizations funded 201

Top Funders — page 4 of 4

171. Vanguard Charitable Endowment ProgramDonor-advised
38 grants to 15 organizations · largest $1.4M · through 2024
$2.0M
172. Network for GoodDonor-advised
37 grants to 14 organizations · largest $91K · through 2024
$857K
173. American Online Giving Foundation IncDonor-advised
47 grants to 21 organizations · largest $122K · through 2024
$729K
174. Morgan Stanley Global Impact Funding Trust IncDonor-advised
27 grants to 13 organizations · largest $40K · through 2024
$313K
175. National Philanthropic TrustDonor-advised
18 grants to 10 organizations · largest $250K · through 2024
$761K
180. Roper St Francis FoundationRegrantor
29 grants to 7 organizations · largest $3.2M · through 2024 · 96.5% of their giving
$24.4M
181. Prisma Health Midlands Foundation F/K/a Palmetto Health FoundationRegrantor
6 grants to 1 organization · largest $6.4M · through 2024 · 100.0% of their giving
$20.1M
182. The Tuomey FoundationRegrantor
7 grants to 2 organizations · largest $3.1M · through 2023 · 96.1% of their giving
$6.8M
183. Roper St Francis HealthcareRegrantor
5 grants to 5 organizations · largest $2.5M · through 2020 · 89.5% of their giving
$5.7M
184. Carefirst Carolina FoundationRegrantor
10 grants to 1 organization · largest $145K · through 2024 · 46.7% of their giving
$791K
185. Challenge to Conquer CancerRegrantor
5 grants to 1 organization · largest $118K · through 2025 · 76.7% of their giving
$511K
186. Make-a-Wish Foundation of AmericaRegrantor
7 grants to 1 organization · largest $1.4M · through 2024 · 1.7% of their giving
$6.1M
187. South Carolina Medical Association FoundationRegrantor
19 grants to 7 organizations · largest $20K · through 2024 · 28.8% of their giving
$380K
188. South Carolina Hospital AssociationRegrantor
24 grants to 15 organizations · largest $38K · through 2020 · 43.2% of their giving
$286K
189. Bishop Gadsden Episcopal Retirement CommunityRegrantor
3 grants to 2 organizations · largest $132K · through 2024 · 18.1% of their giving
$271K
190. The Charles Lea Center Foundation IncRegrantor
20 grants to 1 organization · largest $42K · through 2024 · 90.9% of their giving
$238K
191. United Way of Aiken County IncRegrantor
7 grants to 1 organization · largest $112K · through 2025 · 6.4% of their giving
$694K
192. United Way of Florence CountyRegrantor
11 grants to 1 organization · largest $70K · through 2024 · 9.4% of their giving
$337K
193. Free Medical Clinic of Darlington CountyRegrantor
1 grant to 1 organization · largest $144K · through 2023 · 100.0% of their giving
$144K
194. Curing Kids Cancer IncRegrantor
3 grants to 2 organizations · largest $240K · through 2024 · 5.1% of their giving
$490K
195. Calhoun Traumatic Brain Injury FoundationRegrantor
6 grants to 1 organization · largest $30K · through 2025 · 33.9% of their giving
$100K
196. Louvenia D Barksdale Sickle Cell Anemia FoundatioRegrantor
1 grant to 1 organization · largest $100K · through 2022 · 20.0% of their giving
$100K
197. Prisma Health-MidlandsRegrantor
8 grants to 2 organizations · largest $45K · through 2022 · 7.9% of their giving
$224K
198. River Hillslake Wylie Lions Charities IncRegrantor
4 grants to 1 organization · largest $28K · through 2024 · 19.3% of their giving
$92K
199. United Way of Anderson CountyRegrantor
5 grants to 1 organization · largest $49K · through 2023 · 8.4% of their giving
$188K

Funders are ordered by how much of their overall giving goes to health & medicine work in South Carolina, not by dollar totals alone — a foundation that concentrates its giving here is usually a better prospect than a larger one for which this is a rounding error. 12 of the funders counted here are donor-advised fund sponsors, which grant on behalf of individual donors and accept no applications; they are marked and ranked last.

Other Causes Funded in South Carolina

About This Data

A grant appears here when a funder reported it on its IRS Form 990 and the recipient organization is classified under the NTEE group covering health & medicine work, with an address in South Carolina. Grants are counted from the 2025 filing year backward.

Some 990 grant schedules list a recipient by name and address without an EIN, and those grants cannot be matched to a classification — so the totals above represent identifiable health & medicine funding in South Carolina, not every dollar that reached the sector. Figures are a floor, not a ceiling.

Looking for organizations rather than funders? Browse all nonprofits in South Carolina

Research South Carolina funders in depth

Full grant histories, recipient lists, officer compensation, multi-year financials, and exports for every foundation Imperigo tracks.